Steven Edgar

Steven leads Platform Analytical Chemistry at Octant.  Prior to joining Octant, Steven worked in Business Development at Ginkgo and was an investor at The Production Board after several years as a scientist at Zymergen. Steven holds a PhD from MIT in chemical engineering, where he applied enzymology, chemical synthesis, synthetic biology, and bioinformatics techniques to decipher and modify enzymatic mechanisms.

Publications:

  • Edgar, S, et al. "Engineering of taxadiene synthase for improved selectivity and yield of a key taxol biosynthetic intermediate." ACS synthetic biology 6.2 (2016): 201-205.
  • Edgar, S., Zhou, K., Qiao, K., King, J., & Stephanopoulos, G. “Mechanistic Insights into Taxadiene-5α-Hydroxylase.” ACS chemical biology (2015).
  • Chatzivasileiou, A. O., Ward, V., Edgar, S. M., & Stephanopoulos, G. “Two-step pathway for isoprenoid synthesis”. Proceedings of the National Academy of Sciences, 116(2), (2019).
  • Zhou, K., Qiao, K., Edgar, S., & Stephanopoulos, G. "Distributing a metabolic pathway among a microbial consortium enhances production of natural products." Nature biotechnology (2015).

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