Steven leads Platform Analytical Chemistry at Octant. Prior to joining Octant, Steven worked in Business Development at Ginkgo and was an investor at The Production Board after several years as a scientist at Zymergen. Steven holds a PhD from MIT in chemical engineering, where he applied enzymology, chemical synthesis, synthetic biology, and bioinformatics techniques to decipher and modify enzymatic mechanisms.
Publications:
- Edgar, S, et al. "Engineering of taxadiene synthase for improved selectivity and yield of a key taxol biosynthetic intermediate." ACS synthetic biology 6.2 (2016): 201-205.
- Edgar, S., Zhou, K., Qiao, K., King, J., & Stephanopoulos, G. “Mechanistic Insights into Taxadiene-5α-Hydroxylase.” ACS chemical biology (2015).
- Chatzivasileiou, A. O., Ward, V., Edgar, S. M., & Stephanopoulos, G. “Two-step pathway for isoprenoid synthesis”. Proceedings of the National Academy of Sciences, 116(2), (2019).
- Zhou, K., Qiao, K., Edgar, S., & Stephanopoulos, G. "Distributing a metabolic pathway among a microbial consortium enhances production of natural products." Nature biotechnology (2015).