The next generation of medicine will require bold new approaches native to biology. Octant is navigating the complexity of biology and chemistry to develop next generation small molecules.
Drugging the cellular mechanisms that cause disease
Most drug programs focus on binding molecules to a purified “target” protein, hoping that binding will drive a desired downstream function. Octant engineers biology and chemistry at massive scales to modulate the function itself, targeting complex cellular mechanisms that drive disease. We've focused these efforts internally on correcting diseases of protein misfolding and mistrafficking.
We build custom sensors in human cells to disentangle and model the cellular mechanisms driving disease, for example, how a drug candidate interacting with a misfolded protein is affecting cellular function.
Engineering small molecules to modulate biological mechanisms requires high-throughput explorations of local chemical diversity in living cells.
Barcoded multiplexing enables massively parallel high-throughput drug discovery. Barcoded sensors quantify subtle effect sizes across thousands of experiments, critical for powering direct-to-biology chemistry and large AI/ML datasets.
The Octant platform is enabled, processed, and accelerated by our advanced AI/ML pipelines and tools. Our proprietary chemical biology datasets generate unique insights from millions of data points to advance drug programs.
We are a group of technologists and builders charting new approaches to drug discovery. We combine new technologies to find simple and elegant solutions to complex problems. Scientists, engineers and operators - we are all working together to build a new type of company.
About UsIf you are passionate about next-generation drug discovery, we’d love to hear from you.
ahoy@octant.bio